Amilin 10 mg Tablet 1 Strip 
Item code: 955150 

Indications 

Pharmacology 
The mechanism of action of this drug is not fully elucidated. It is suggested that amitriptyline inhibits the membrane pump mechanism responsible for the re-uptake of transmitter amines, such as norepinephrine and serotonin, thereby increasing their concentration at the synaptic clefts of the brain. These amines are important in regulating mood. The monoamine hypothesis in depression, one of the oldest hypotheses, postulates that deficiencies of serotonin (5-HT) and/or norepinephrine (NE) neurotransmission in the brain lead to depressive effects. This drug counteracts these mechanisms, and this may be the mechanism of amitriptyline in improving depressive symptoms. Whether its analgesic effects are related to its mood-altering activities or attributable to a different, less obvious pharmacological action (or a combination of both) is unknown.

Dosage & Administration

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Storage Conditions
Store in a cool and dry place, below 30°C. Protect from light and moisture.

Side Effects

• Anticholinergic: Excessive perspiration, dry mouth, blurred vision, hyperpyrexia, urinary retention and urinary tract dilatation.
• Cardiovascular reactions: Hypotension, syncope, postural hypotension, hypertension, tachycardia, palpitations, myocardial infarction, etc.
• CNS and Neuromuscular: Confusional states, disturbed concentration, disorientation, delusions, etc.
• Allergic: Skin rash, urticaria, photosensitization, etc.
• Haematological: Bone-marrow depression.
• Gastrointestinal: Nausea, epigastric distress, vomiting, anorexia, stomatitis, unpleasant taste, weight loss, diarrhoea, constipation, etc.
• Endocrine: Testicular swelling, gynaecomastia, breast enlargement, galactorrhoea, etc.

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